Niisa sails 10 routes between 15 ports in Greenland, mostly Ilulissat, Qeqertarsuaq and Qasigiannguit. From Ilulissat: Qeqertarsuaq, Qasigiannguit, Qeqertaq, Ilimanaq and Saqqaq. From Qeqertarsuaq: Qasigiannguit. From Qasigiannguit: Aasiaat, Ikamiut and Akunnaaq. From Aasiaat: Qeqertarsuaq, Iginniarfik, Kangaatsiaq, Niaqornaarsuk, Kitsissuarsuit, Ikerasaarsuk and Attu.